A therapeutic HIV vaccine: how good is good enough?

Good enough to use for research, but not good enough to benefit from the results of that research: are the clinical HIV vaccine trials in Africa unjust?

A Shot at Dendritic Cell-Based Vaccine Strategy against HIV-1

Introduction: Despite considerable efforts to control AIDS pandemic, it is still one of the significant infectious concerns worldwide. The advance in medical research has led to the development of highly active antiretroviral therapy with a considerable effect to suppress the disease. However, an effective vaccine capable of eradication the HIV pandemic is not available yet. Failure to develop ...

Department of medical education; A personal history

This is a brief overview of the history of formal introduction of the art andscience of education into the sphere of medical education in Shiraz. Before this introduction medical education was, and in the majority of other institutions world-wide still is, a simple transfer of knowledge from teacher to student. The students accepted their passive role because this was how they had been taught a...

Willingness to Participate in HIV Therapeutic Vaccine Trials among HIV-Infected Patients on ART in China

BACKGROUND More and more HIV therapeutic vaccines will enter clinical trials; however, little is known about the willingness to participate (WTP) in HIV therapeutic vaccine trials among HIV-positive individuals. OBJECTIVE To investigate the WTP in HIV therapeutic vaccine trials among Chinese HIV-infected patients. METHODS We conducted a cross-sectional survey on HIV-positive inpatients and ...

Machine Learning Approaches in Drug Development of HIV/AIDS

III. Involving T-cell responses: Another therapeutic vaccine in development is designed to include CD4+ T cell responses in HIV infected people. CD4+ T cells play a important role in immune protection against viral infections. Deficits in CD4+ t cells are associated with virus reactivation, vulnerability to opportunistic infections and poor vaccine efficacy. For HIV/ AIDS, the introduction of n...